- accession:NM_001256080
- 基因别名:KLK2
- 基因描述:Homo sapiens kallikrein-related peptidase 2 (KLK2), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:480
- 翻译后氨基酸长度:159
- TranscriptVariant:This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1.
- 基因简介:This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
- 规格:10ul 质粒
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