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- accession：NM_148887
- 基因别名：MRPL10
- 基因描述：Homo sapiens mitochondrial ribosomal protein L10 (MRPL10), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：816
- 翻译后氨基酸长度：271
- TranscriptVariant：This variant (2) includes an additional coding region exon, compared to variant 1, that results in a longer protein (isoform b) with a longer and distinct N-terminus, compared to isoform a. The predicted protein does not contain a possible mitochondrial transit peptide sequence. A uORF with strong Kozak signal exists, but its length is short enough (18 aa) that it is not expected to interfere with translation from the longer, downstream ORF of 271 aa.
- 基因简介：Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
