- accession:NM_030960
- 基因别名:SPACA1
- 基因描述:Homo sapiens sperm acrosome associated 1 (SPACA1), mRNA.
- 载体:现货载体
- CDS区长度:885
- 翻译后氨基酸长度:294
- 基因简介:The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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