- accession:NM_002468
- 基因别名:MYD88
- 基因描述:Homo sapiens myeloid differentiation primary response 88 (MYD88), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:930
- 翻译后氨基酸长度:309
- TranscriptVariant:This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
- 基因简介:This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
- 规格:10ul 质粒
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