- accession:NM_001267057
- 基因别名:CASP7
- 基因描述:Homo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant f, mRNA.
- 载体:现货载体
- CDS区长度:1167
- 翻译后氨基酸长度:388
- TranscriptVariant:This variant (f) lacks an internal exon in the 5' region and initiates translation at an alternate upstream start codon, compared to variant d. The encoded isoform (e) is longer and has a distinct N-terminus, compared to isoform delta.
- 基因简介:This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- 规格:10ul 质粒
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