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- accession：NM_001005377
- 基因别名：PLAUR
- 基因描述：Homo sapiens plasminogen activator, urokinase receptor (PLAUR), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：873
- 翻译后氨基酸长度：290
- TranscriptVariant：This variant (3) lacks one exon in the coding region and encodes an isoleucine rather than a valine following the splice site, compared to variant 1. Variant 3 encodes isoform 3 which is longer and lacks one of three LU (Ly-6 antigen/uPA receptor-like) domains, compared to isoform 2.
- 基因简介：This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
