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- accession：NM_001206801
- 基因别名：RFC5
- 基因描述：Homo sapiens replication factor C (activator 1) 5, 36.5kDa (RFC5), transcript variant 5, mRNA.
- 载体：现货载体
- CDS区长度：1014
- 翻译后氨基酸长度：337
- TranscriptVariant：This variant (5) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (4) that is shorter than isoform 1.
- 基因简介：The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9. [provided by RefSeq, May 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
