- accession:NM_004562
- 基因别名:PARK2
- 基因描述:Homo sapiens parkin RBR E3 ubiquitin protein ligase (PARK2), transcript variant 1, mRNA.
- 载体:pEGFP-C1、pLVX-Puro、plvx-3xflag-puro、pCDNA3.1-mCherry-C
- CDS区长度:1398
- 翻译后氨基酸长度:465
- TranscriptVariant:Transcript variant 1 represents the predominant and full-length form of this gene.
- 基因简介:The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列