- accession:NM_001243224
- 基因别名:RAD9A
- 基因描述:Homo sapiens RAD9 homolog A (S. pombe) (RAD9A), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:948
- 翻译后氨基酸长度:315
- TranscriptVariant:This variant (2) contains an alternate 5' terminal exon (with an in-frame AUG) compared to variant 1. This results in a a shorter isoform (2) with a distinct N-terminus compared to isoform 1.
- 基因简介:This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
- 规格:10ul 质粒
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