- accession:NM_000321
- 基因别名:RB1
- 基因描述:Homo sapiens retinoblastoma 1 (RB1), mRNA.
- 载体: 现货载体
- CDS区长度:2787
- 翻译后氨基酸长度:928
- 基因简介:The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列