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人PRKCH(NM_006255)ORF克隆
人PRKCH(NM_006255)ORF克隆
  • 商品货号:FO106683
  • 已售 8 件 | 评价 0 人次 | 关注度 456
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    • accession:NM_006255
    • 基因别名:PRKCH
    • 基因描述:Homo sapiens protein kinase C, eta (PRKCH), mRNA.
    • 载体: 现货载体
    • CDS区长度:2052
    • 翻译后氨基酸长度:683
    • 基因简介:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列