- accession:NM_001206703
- 基因别名:SP100
- 基因描述:Homo sapiens SP100 nuclear antigen (SP100), transcript variant 5, mRNA.
- 载体:现货载体
- CDS区长度:1359
- 翻译后氨基酸长度:452
- TranscriptVariant:This variant (5) differs in the 3' UTR and has multiple differences in the coding region, compared to variant 1. The resulting isoform (5) lacks two internal segments and has a much shorter and distinct C-terminus, compared to isoform 1.
- 基因简介:This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011]
- 规格:10ul 质粒
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