• accession：NM_003958
• 基因别名：RNF8
• 基因描述：Homo sapiens ring finger protein 8， E3 ubiquitin protein ligase (RNF8)， transcript variant 1， mRNA.
• 载体：pcDNA3.1-3xFlag-N
• CDS区长度：1458
• 翻译后氨基酸长度：485
• TranscriptVariant：This variant (1) represents the most abundant transcript and encodes the longer isoform (1).
• 基因简介：The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2)， including UBE2E1/UBCH6， UBE2E2， and UBE2E3， and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq， Feb 2012]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGGGGAGCCCGGCTTCTTCGTCACAGGAGACCGCGCCGGTGGCCGGAGCTGGTGCCTGCGGCGGGTGG
GGATGAGCGCCGGGTGGCTGCTGCTGGAAGATGGGTGCGAGGTGACTGTAGGACGAGGATTTGGTGTCAC
ATACCAACTGGTATCAAAAATCTGCCCCCTGATGATTTCTCGAAACCACTGTGTTTTGAAGCAGAATCCT
GAGGGCCAATGGACAATTATGGACAACAAGAGTCTAAATGGTGTTTGGCTGAACAGAGCGCGTCTGGAAC
CTTTAAGGGTCTATTCCATTCATCAGGGAGACTACATCCAACTTGGAGTGCCTCTGGAAAATAAGGAGAA
TGCGGAGTATGAATATGAAGTTACTGAAGAAGACTGGGAGACAATATATCCTTGTCTTTCCCCAAAGAAT
GACCAAATGATAGAAAAAAATAAGGAATTGAGAACTAAAAGGAAATTCAGTTTGGATGAATTAGCAGGTC
CTGGAGCTGAAGGCCCCTCAAATTTGAAATCCAAAATAAATAAAGTGTCTTGTGAATCTGGTCAGCCAGT
GAAATCACAGGGGAAAGGTGAAGTGGCCAGTACACCCTCTGACAATTTGGATCCTAAGTTGACTGCCCTT
GAGCCAAGTAAGACCACAGGGGCTCCCATTTACCCTGGCTTCCCCAAAGTCACAGAGGTTCATCATGAGC
AGAAAGCCTCAAACTCTTCAGCATCTCAGAGAAGCTTACAGATGTTTAAGGTGACCATGTCCAGGATTCT
GAGGCTCAAAATACAGATGCAGGAAAAACATGAAGCCGTTATGAATGTGAAAAAGCAGACCCAAAAGGGG
AACTCAAAGAAAGTTGTGCAAATGGAGCAGGAACTTCAGGACTTACAGTCCCAGCTGTGTGCAGAGCAGG
CTCAGCAGCAGGCAAGAGTGGAGCAACTAGAGAAGACTTTCCAGGAAGAGGAACAGCATCTTCAGGGTTT
GGAGATAGCCCAAGGAGAAAAGGACCTGAAGCAACAGCTGGCCCAGGCTCTGCAGGAGCATTGGGCTCTA
ATGGAAGAGCTAAATCGCAGCAAGAAGGACTTTGAAGCAATCATTCAAGCCAAGAACAAAGAATTAGAGC
AGACCAAGGAAGAGAAGGAGAAGATGCAAGCACAGAAGGAAGAAGTTCTTAGCCACATGAATGATGTGCT
AGAGAATGAGCTCCAATGTATTATTTGTTCAGAATACTTCATTGAGGCTGTCACCTTGAACTGTGCCCAC
AGTTTCTGCTCCTACTGTATCAATGAATGGATGAAGCGGAAGATAGAATGCCCCATTTGTCGGAAGGACA
TTAAGTCCAAAACGTACTCTTTGGTTCTGGACAATTGCATTAATAAGATGGTAAATAATCTGAGCTCAGA
AGTGAAAGAACGACGAATTGTTCTCATTAGGGAACGAAAAGCAAAGAGATTGTTCTGA

翻译后氨基酸参数序列： 点击查看序列

ATGGGGGAGCCCGGCTTCTTCGTCACAGGAGACCGCGCCGGTGGCCGGAGCTGGTGCCTGCGGCGGGTGG
GGATGAGCGCCGGGTGGCTGCTGCTGGAAGATGGGTGCGAGGTGACTGTAGGACGAGGATTTGGTGTCAC
ATACCAACTGGTATCAAAAATCTGCCCCCTGATGATTTCTCGAAACCACTGTGTTTTGAAGCAGAATCCT
GAGGGCCAATGGACAATTATGGACAACAAGAGTCTAAATGGTGTTTGGCTGAACAGAGCGCGTCTGGAAC
CTTTAAGGGTCTATTCCATTCATCAGGGAGACTACATCCAACTTGGAGTGCCTCTGGAAAATAAGGAGAA
TGCGGAGTATGAATATGAAGTTACTGAAGAAGACTGGGAGACAATATATCCTTGTCTTTCCCCAAAGAAT
GACCAAATGATAGAAAAAAATAAGGAATTGAGAACTAAAAGGAAATTCAGTTTGGATGAATTAGCAGGTC
CTGGAGCTGAAGGCCCCTCAAATTTGAAATCCAAAATAAATAAAGTGTCTTGTGAATCTGGTCAGCCAGT
GAAATCACAGGGGAAAGGTGAAGTGGCCAGTACACCCTCTGACAATTTGGATCCTAAGTTGACTGCCCTT
GAGCCAAGTAAGACCACAGGGGCTCCCATTTACCCTGGCTTCCCCAAAGTCACAGAGGTTCATCATGAGC
AGAAAGCCTCAAACTCTTCAGCATCTCAGAGAAGCTTACAGATGTTTAAGGTGACCATGTCCAGGATTCT
GAGGCTCAAAATACAGATGCAGGAAAAACATGAAGCCGTTATGAATGTGAAAAAGCAGACCCAAAAGGGG
AACTCAAAGAAAGTTGTGCAAATGGAGCAGGAACTTCAGGACTTACAGTCCCAGCTGTGTGCAGAGCAGG
CTCAGCAGCAGGCAAGAGTGGAGCAACTAGAGAAGACTTTCCAGGAAGAGGAACAGCATCTTCAGGGTTT
GGAGATAGCCCAAGGAGAAAAGGACCTGAAGCAACAGCTGGCCCAGGCTCTGCAGGAGCATTGGGCTCTA
ATGGAAGAGCTAAATCGCAGCAAGAAGGACTTTGAAGCAATCATTCAAGCCAAGAACAAAGAATTAGAGC
AGACCAAGGAAGAGAAGGAGAAGATGCAAGCACAGAAGGAAGAAGTTCTTAGCCACATGAATGATGTGCT
AGAGAATGAGCTCCAATGTATTATTTGTTCAGAATACTTCATTGAGGCTGTCACCTTGAACTGTGCCCAC
AGTTTCTGCTCCTACTGTATCAATGAATGGATGAAGCGGAAGATAGAATGCCCCATTTGTCGGAAGGACA
TTAAGTCCAAAACGTACTCTTTGGTTCTGGACAATTGCATTAATAAGATGGTAAATAATCTGAGCTCAGA
AGTGAAAGAACGACGAATTGTTCTCATTAGGGAACGAAAAGCAAAGAGATTGTTCTGA