×
![]()
- accession：NM_001204401
- 基因别名：XIAP
- 基因描述：Homo sapiens X-linked inhibitor of apoptosis (XIAP), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1494
- 翻译后氨基酸长度：497
- TranscriptVariant：This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
- 基因简介：This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
