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- accession：NM_001093771
- 基因别名：TXNRD1
- 基因描述：Homo sapiens thioredoxin reductase 1 (TXNRD1), transcript variant 5, mRNA.
- 载体：现货载体
- CDS区长度：1950
- 翻译后氨基酸长度：649
- TranscriptVariant：This variant (5) encodes the longest isoform (3). This variant appears to be expressed primarily in the testis.
- 基因简介：This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
