- accession:NM_001193270
- 基因别名:MSL3
- 基因描述:Homo sapiens male-specific lethal 3 homolog (Drosophila) (MSL3), transcript variant 5, mRNA.
- 载体:现货载体
- CDS区长度:1530
- 翻译后氨基酸长度:509
- TranscriptVariant:This variant (5) differs in the 5' UTR and 5' coding region, and uses a distinct start codon, compared to variant 1. The resulting isoform (e) has a distinct N-terminus and is 12 aa shorter than isoform a.
- 基因简介:This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
- 规格:10ul 质粒
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