- accession:NM_032621
- 基因别名:BEX2
- 基因描述:Homo sapiens brain expressed X-linked 2 (BEX2), transcript variant 3, mRNA.
- 载体: 现货载体
- CDS区长度:387
- 翻译后氨基酸长度:128
- TranscriptVariant:This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3 and 4 encode the same isoform (3).
- 基因简介:This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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