- accession:NM_001165975
- 基因别名:PDE1B
- 基因描述:Homo sapiens phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1551
- 翻译后氨基酸长度:516
- TranscriptVariant:This variant (2) contains an alternate 5' terminal exon (with an AUG codon) compared to variant 1. This results in a shorter isoform (2) with a distinct N-terminus compared to isoform 1.
- 基因简介:The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
- 规格:10ul 质粒
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