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人 SIRT1 (NM_012238) cDNA克隆
人 SIRT1 (NM_012238) cDNA克隆
  • 商品货号:FC114254
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    • accession:NM_012238
    • 基因别名:SIRT1
    • 基因描述:Homo sapiens sirtuin 1 (SIRT1), transcript variant 1, mRNA.
    • 载体:现货载体
    • CDS区长度:2244
    • 翻译后氨基酸长度:747
    • TranscriptVariant:This variant (1) represents the longer transcript and encodes the longer isoform (a).
    • 基因简介:This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列