- accession:NM_001199763
- 基因别名:PTPRN
- 基因描述:Homo sapiens protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2853
- 翻译后氨基酸长度:950
- TranscriptVariant:This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- 基因简介:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
- 规格:10ul 质粒
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