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- 商品货号：G112782
- accession：NM_001243835
- 基因别名：STAT4
- 基因描述：Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：2247
- 翻译后氨基酸长度：748
- TranscriptVariant：This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
- 基因简介：The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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