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- accession：NM_001195055
- 基因别名：DDIT3
- 基因描述：Homo sapiens DNA-damage-inducible transcript 3 (DDIT3), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：579
- 翻译后氨基酸长度：192
- TranscriptVariant：This variant (3) lacks an internal segment in the 5' UTR, as compared to variant 1. Variants 1-4 encode the same isoform 1.
- 基因简介：This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
