- accession:NM_139157
- 基因别名:ST5
- 基因描述:Homo sapiens suppression of tumorigenicity 5 (ST5), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2154
- 翻译后氨基酸长度:717
- TranscriptVariant:This variant (2), also known as p82, lacks an in-frame exon in the coding region, as compared to variant 1. It encodes isoform 2 that is missing an internal segment, as compared to isoform 1.
- 基因简介:This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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