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- accession：NM_213560
- 基因别名：PKN1
- 基因描述：Homo sapiens protein kinase N1 (PKN1), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：2847
- 翻译后氨基酸长度：948
- TranscriptVariant：This variant (1) encodes the longer isoform (1).
- 基因简介：The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
