- accession:NM_001699
- 基因别名:AXL
- 基因描述:Homo sapiens AXL receptor tyrosine kinase (AXL), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2658
- 翻译后氨基酸长度:885
- TranscriptVariant:This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter than isoform 1.
- 基因简介:The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
- 规格:10ul 质粒
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