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- accession：NM_005231
- 基因别名：CTTN
- 基因描述：Homo sapiens cortactin (CTTN), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：1653
- 翻译后氨基酸长度：550
- TranscriptVariant：This variant (1) is the longest transcript.
- 基因简介：This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
