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人 ACVR1C (NM_001111031) cDNA克隆
人 ACVR1C (NM_001111031) cDNA克隆
  • 商品货号:FC117115
  • 已售 4 件 | 评价 0 人次 | 关注度 345
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    • accession:NM_001111031
    • 基因别名:ACVR1C
    • 基因描述:Homo sapiens activin A receptor, type IC (ACVR1C), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:1332
    • 翻译后氨基酸长度:443
    • TranscriptVariant:This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2), also known as tALK7, has a shorter N-terminus when compared to isoform 1, and lacks part of the activin receptor-binding domain.
    • 基因简介:ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列