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人 ACVR1C (NM_001111033) cDNA克隆
人 ACVR1C (NM_001111033) cDNA克隆
  • 商品货号:FC117117
  • 已售 4 件 | 评价 0 人次 | 关注度 369
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    • accession:NM_001111033
    • 基因别名:ACVR1C
    • 基因描述:Homo sapiens activin A receptor, type IC (ACVR1C), transcript variant 4, mRNA.
    • 载体:现货载体
    • CDS区长度:1011
    • 翻译后氨基酸长度:336
    • TranscriptVariant:This variant (4) lacks two alternate in-frame exons in the coding region, compared to variant 1. The resulting isoform (4), also known as sALK7b, lacks the transmembrane domain, GS domain, and part of the kinase domain, compared to isoform 1.
    • 基因简介:ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列