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- accession：NM_173060
- 基因别名：CAST
- 基因描述：Homo sapiens calpastatin (CAST), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：2061
- 翻译后氨基酸长度：686
- TranscriptVariant：This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 6. This variant also contains an in-frame exon compared to variant 6. The encoded isoform (b) is shorter than isoform f.
- 基因简介：The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
