• accession：NM_001177693
• 基因别名：ARHGEF28
• 基因描述：Homo sapiens Rho guanine nucleotide exchange factor (GEF) 28 (ARHGEF28), transcript variant 2, mRNA.
• 载体：现货载体
• CDS区长度：5118
• 翻译后氨基酸长度：1705
• TranscriptVariant：This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
• 基因简介：This gene encodes a member of the Rho guanine nucleotide exchange factor family. The encoded protein interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGAGTTGAGCTGCAGCGAAGCACCTCTTTACGGGCAGATGATGATCTATGCGAAGTTTGACAAAAATG
TGTATCTTCCTGAAGATGCTGAGTTTTACTTTACTTATGACGGATCTCATCAGCGACATGTCATGATTGC
AGAGCGCATCGAGGATAACGTTCTCCAGTCCAGCGTCCCAGGCCATGGGCTTCAGGAGACGGTGACGGTA
TCTGTGTGCCTCTGCTCGGAAGGTTACTCTCCGGTGACCATGGGCTCTGGCTCAGTGACCTACGTGGACA
ACATGGCTTGCAGGCTGGCTCGTCTGCTGGTGACGCAGGCCAATCGCCTCACAGCCTGCAGCCACCAGAC
CCTGCTGACCCCATTTGCCTTGACGGCAGGAGCACTGCCTGCCTTGGATGAGGAGCTCGTGCTGGCTCTG
ACCCATCTGGAATTGCCTCTAGAGTGGACTGTGTTGGGAAGTTCTTCACTTGAAGTATCTTCTCACAGAG
AATCTCTTCTACACCTGGCTATGAGATGGGGCCTGGCTAAACTTTCCCAGTTCTTCTTGTGTCTCCCGGG
GGGAGTCCAGGCCTTGGCTTTACCCAACGAAGAGGGTGCCACACCATTAGACTTAGCTTTACGTGAAGGA
CACTCCAAGCTGGTGGAAGACGTCACAAATTTTCAGGGCAGATGGTCCCCAAGCTTCTCCCGAGTGCAGC
TCAGTGAAGAAGCCTCCTTGCATTACATTCACTCATCGGAAACGCTGACCCTGACCCTGAACCACACAGC
CGAGCATTTGTTGGAGGCAGATATTAAACTCTTCCGGAAATACTTTTGGGATAGAGCCTTTCTTGTCAAG
GCCTTTGAGCCAGAAGCCAGGCCAGAGGAAAGAACAGCTATGCCCTCCAGCGGTGCAGAAACTGAAGAAG
AGATTAAGAATTCAGTGTCCAGCAGATCAGCAGCTGAAAAGGAAGATATAAAGCGTGTCAAAAGCCTGGT
GGTTCAACACAATGAACATGAAGACCAGCACAGCCTAGATTTGGATCGCTCCTTCGATATCCTAAAAAAA
TCCAAGCCGCCCTCGACATTGCTTGCTGCAGGCCGGCTTTCAGACATGCTGAATGGAGGTGATGAAGTCT
ACGCTAACTGTATGGTGATTGATCAGGTTGGTGATTTGGATATCAGCTATATTAATATAGAGGGAATCAC
TGCCACTACCAGCCCTGAATCCAGAGGTTGCACTCTGTGGCCTCAGAGCAGCAAACACACCCTTCCTACA
GAAACCAGTCCCAGTGTGTACCCACTTAGTGAAAATGTCGAAGGGACAGCACACACTGAAGCCCAGCAGT
CCTTCATGTCACCATCAAGTTCGTGTGCTTCCAACTTGAATCTTTCTTTTGGTTGGCATGGATTTGAAAA
GGAACAAAGTCATCTAAAGAAAAGAAGTTCTAGCCTTGATGCCTTGGACGCCGACAGTGAAGGGGAAGGG
CATTCTGAGCCATCCCACATCTGTTACACTCCAGGGTCTCAGAGCTCCTCAAGAACTGGGATTCCTAGTG
GGGATGAATTGGACTCTTTTGAGACTAACACTGAACCGGATTTTAATATCTCCAGGGCTGAATCCCTTCC
TCTATCAAGTAATCTACAGTCGAAGGAATCACTGCTTTCTGGAGTTCGCTCACGTTCTTATTCTTGCTCA
TCACCCAAAATTTCTTTAGGAAAAACTCGTTTGGTGCGTGAATTAACAGTATGCAGTTCAAGTGAAGAGC
AAAGAGCTTACAGCTTATCGGAGCCACCAAGAGAAAACAGAATTCAGGAAGAAGAATGGGATAAATACAT
CATACCTGCCAAATCAGAGTCTGAAAAATATAAAGTGAGTCGAACTTTCAGTTTCCTCATGAATAGGATG
ACTAGCCCTCGGAATAAATCAAAGACAAAAAGCAAGGATGCCAAAGATAAAGAGAAGCTGAATCGACATC
AGTTTGCCCCAGGAACATTCTCTGGGGTTCTGCAGTGTTTGGTTTGTGATAAAACACTCCTGGGGAAAGA
GTCACTGCAGTGTTCTAACTGTAATGCAAATGTGCACAAAGGTTGTAAAGATGCTGCGCCTGCATGCACC
AAGAAATTCCAAGAGAAATATAACAAGAACAAACCACAGACCATCCTTGGAAATTCTTCATTTAGAGACA
TCCCACAGCCTGGTCTCTCCTTGCACCCTTCTTCCTCCGTGCCTGTTGGATTGCCGACTGGAAGGAGGGA
GACTGTGGGACAGGTCCATCCATTGTCCAGAAGTGTTCCAGGCACCACCTTGGAAAGCTTCAGGAGGTCA
GCCACATCCTTGGAGTCTGAGAGTGACCATAACAGCTGCAGAAGCAGGTCTCATTCTGATGAGCTGCTAC
AGTCCATGGGCTCTTCTCCCTCTACAGAGTCTTTCATAATGGAAGATGTTGTGGATTCTTCTCTGTGGAG
TGACCTCAGCAGTGATGCCCAGGAGTTTGAAGCAGAATCTTGGAGTCTTGTGGTGGATCCCTCATTTTGT
AATAGGCAGGAGAAGGATGTCATCAAAAGACAGGATGTCATTTTTGAGCTAATGCAAACAGAGATGCATC
ACATCCAGACCCTGTTCATCATGTCTGAGATCTTCAGGAAAGGCATGAAAGAGGAGCTGCAGCTGGACCA
CAGCACCGTGGATAAAATTTTCCCCTGTTTAGATGAGTTGCTTGAAATCCACAGGCATTTCTTCTACAGT
ATGAAGGAACGAAGGCAGGAATCCTGTGCTGGCAGCGACAGGAATTTTGTGATCGACCGAATTGGAGATA
TTTTGGTACAACAGTTTTCAGAAGAAAATGCAAGTAAAATGAAGAAAATATATGGAGAATTCTGTTGCCA
TCATAAAGAAGCTGTTAACCTCTTTAAAGAACTCCAGCAGAATAAAAAGTTTCAGAATTTTATTAAGCTC
CGAAATAGTAATCTTTTGGCTCGACGCCGAGGAATTCCAGAATGCATTCTGTTGGTCACTCAGCGTATTA
CAAAATACCCTGTCTTGGTGGAAAGGATATTGCAGTACACAAAGGAAAGAACTGAGGAACATAAAGACTT
ACGCAAAGCGCTTTGCTTAATTAAAGACATGATTGCAACAGTGGATTTAAAAGTCAATGAATATGAGAAA
AACCAAAAATGGCTTGAGATCCTAAATAAGATTGAAAACAAAACATACACGAAGCTCAAAAATGGACATG
TGTTTAGGAAGCAGGCACTGATGAGTGAAGAAAGGACTCTGTTATATGATGGCCTTGTTTACTGGAAAAC
TGCTACAGGTCGTTTCAAAGATATCCTAGCTCTACTTCTAACTGATGTGCTGCTCTTTTTACAAGAAAAA
GACCAGAAATACATCTTTGCAGCCGTTGATCAGAAGCCATCAGTTATTTCCCTTCAAAAGCTTATTGCTA
GAGAAGTTGCTAATGAGGAGAGAGGAATGTTTCTGATCAGTGCTTCATCTGCTGGTCCTGAGATGTATGA
AATTCACACCAATTCCAAGGAGGAACGCAATAACTGGATGAGACGGATCCAGCAGGCTGTAGAAAGTTGT
CCTGAAGAAAAAGGGGGAAGGACAAGTGAATCTGATGAAGACAAGAGGAAAGCTGAAGCCAGAGTGGCCA
AAATTCAGCAATGTCAAGAAATACTCACTAACCAAGACCAACAAATTTGTGCGTATTTGGAGGAGAAGCT
GCATATCTATGCTGAACTTGGAGAACTGAGCGGATTTGAGGACGTCCATCTAGAGCCCCACCTCCTTATT
AAACCTGACCCAGGCGAGCCTCCCCAGGCAGCCTCATTACTGGCAGCAGCACTGAAAGAAGCTGAGAGCC
TACAAGTTGCAGTGAAGGCCTCACAGATGGGCGCCGTGAGTCAATCATGTGAGGACAGTTGTGGAGACTC
TGTCTTGGCGGACACACTCAGTTCTCATGATGTACCAGGATCACCGACTGCCTCATTAGTCACAGGAGGG
AGAGAAGGAAGAGGCTGTTCGGATGTGGATCCCGGGATCCAGGGTGTGGTAACCGACTTGGCCGTCTCTG
ATGCAGGGGAGAAGGTGGAATGTAGAAATTTTCCAGGTTCTTCACAATCAGAGATTATACAAGCCATACA
GAATTTAACCCGTCTCTTATACAGCCTTCAGGCCGCCTTGACCATTCAGGACAGCCACATTGAGATCCAC
AGGCTGGTTCTCCAGCAGCAGGAGGGCCTGTCTCTCGGCCACTCTATCCTCCGAGGCGGCCCCTTGCAGG
ACCAGAAGTCTCGCGACGCGGACAGGCAGCATGAGGAGCTGGCCAATGTGCACCAGCTTCAGCACCAGCT
CCAGCAGGAGCAGCGGCGCTGGCTGCGCAGGTGTGAGCAGCAGCAGCGGGCGCAGGCGACCAGGGAGAGC
TGGCTGCAGGAGCGGGAGCGGGAGTGCCAGTCGCAGGAGGAGCTGCTGCTGCGGAGCCGGGGCGAGCTGG
ACCTCCAGCTCCAGGAGTACCAGCACAGCCTGGAGCGGCTGAGGGAGGGCCAGCGCCTGGTGGAGAGGGA
GCAGGCGAGGATGCGGGCCCAGCAGAGCCTGCTGGGCCACTGGAAGCACGGCCGGCAGAGGAGCCTGCCC
GCGGTGCTCCTTCCGGGTGGCCCCGAGGTAATGGAACTTAATCGATCTGAGAGTTTATGTCATGAAAACT
CATTCTTCATCAATGAAGCTTTAGTACAAATGTCATTTAACACTTTCAACAAACTGAATCCATCAGTTAT
CCATCAGGATGCCACTTACCCTACAACTCAATCTCATTCTGACTTGGTGAGGACTAGTGAACATCAAGTA
GACCTCAAGGTGGACCCTTCTCAGCCTTCGAATGTCAGTCACAAACTGTGGACAGCCGCTGGTTCCGGCC
ATCAGATACTTCCTTTCCATGAAAGCAGCAAGGATTCTTGTAAAAATGATTTGGACACCTCCCACACTGA
GTCCCCAACCCCCCATGACTCAAATTCACACCGCCCTCAACTGCAGGCGTTTATAACAGAAGCAAAGCTA
AATCTACCGACAAGGACAATGACCAGACAAGATGGGGAAACTGGAGATGGAGCCAAAGAAAATATTGTTT
ACCTCTAA

翻译后氨基酸参数序列： 点击查看序列

ATGGAGTTGAGCTGCAGCGAAGCACCTCTTTACGGGCAGATGATGATCTATGCGAAGTTTGACAAAAATG
TGTATCTTCCTGAAGATGCTGAGTTTTACTTTACTTATGACGGATCTCATCAGCGACATGTCATGATTGC
AGAGCGCATCGAGGATAACGTTCTCCAGTCCAGCGTCCCAGGCCATGGGCTTCAGGAGACGGTGACGGTA
TCTGTGTGCCTCTGCTCGGAAGGTTACTCTCCGGTGACCATGGGCTCTGGCTCAGTGACCTACGTGGACA
ACATGGCTTGCAGGCTGGCTCGTCTGCTGGTGACGCAGGCCAATCGCCTCACAGCCTGCAGCCACCAGAC
CCTGCTGACCCCATTTGCCTTGACGGCAGGAGCACTGCCTGCCTTGGATGAGGAGCTCGTGCTGGCTCTG
ACCCATCTGGAATTGCCTCTAGAGTGGACTGTGTTGGGAAGTTCTTCACTTGAAGTATCTTCTCACAGAG
AATCTCTTCTACACCTGGCTATGAGATGGGGCCTGGCTAAACTTTCCCAGTTCTTCTTGTGTCTCCCGGG
GGGAGTCCAGGCCTTGGCTTTACCCAACGAAGAGGGTGCCACACCATTAGACTTAGCTTTACGTGAAGGA
CACTCCAAGCTGGTGGAAGACGTCACAAATTTTCAGGGCAGATGGTCCCCAAGCTTCTCCCGAGTGCAGC
TCAGTGAAGAAGCCTCCTTGCATTACATTCACTCATCGGAAACGCTGACCCTGACCCTGAACCACACAGC
CGAGCATTTGTTGGAGGCAGATATTAAACTCTTCCGGAAATACTTTTGGGATAGAGCCTTTCTTGTCAAG
GCCTTTGAGCCAGAAGCCAGGCCAGAGGAAAGAACAGCTATGCCCTCCAGCGGTGCAGAAACTGAAGAAG
AGATTAAGAATTCAGTGTCCAGCAGATCAGCAGCTGAAAAGGAAGATATAAAGCGTGTCAAAAGCCTGGT
GGTTCAACACAATGAACATGAAGACCAGCACAGCCTAGATTTGGATCGCTCCTTCGATATCCTAAAAAAA
TCCAAGCCGCCCTCGACATTGCTTGCTGCAGGCCGGCTTTCAGACATGCTGAATGGAGGTGATGAAGTCT
ACGCTAACTGTATGGTGATTGATCAGGTTGGTGATTTGGATATCAGCTATATTAATATAGAGGGAATCAC
TGCCACTACCAGCCCTGAATCCAGAGGTTGCACTCTGTGGCCTCAGAGCAGCAAACACACCCTTCCTACA
GAAACCAGTCCCAGTGTGTACCCACTTAGTGAAAATGTCGAAGGGACAGCACACACTGAAGCCCAGCAGT
CCTTCATGTCACCATCAAGTTCGTGTGCTTCCAACTTGAATCTTTCTTTTGGTTGGCATGGATTTGAAAA
GGAACAAAGTCATCTAAAGAAAAGAAGTTCTAGCCTTGATGCCTTGGACGCCGACAGTGAAGGGGAAGGG
CATTCTGAGCCATCCCACATCTGTTACACTCCAGGGTCTCAGAGCTCCTCAAGAACTGGGATTCCTAGTG
GGGATGAATTGGACTCTTTTGAGACTAACACTGAACCGGATTTTAATATCTCCAGGGCTGAATCCCTTCC
TCTATCAAGTAATCTACAGTCGAAGGAATCACTGCTTTCTGGAGTTCGCTCACGTTCTTATTCTTGCTCA
TCACCCAAAATTTCTTTAGGAAAAACTCGTTTGGTGCGTGAATTAACAGTATGCAGTTCAAGTGAAGAGC
AAAGAGCTTACAGCTTATCGGAGCCACCAAGAGAAAACAGAATTCAGGAAGAAGAATGGGATAAATACAT
CATACCTGCCAAATCAGAGTCTGAAAAATATAAAGTGAGTCGAACTTTCAGTTTCCTCATGAATAGGATG
ACTAGCCCTCGGAATAAATCAAAGACAAAAAGCAAGGATGCCAAAGATAAAGAGAAGCTGAATCGACATC
AGTTTGCCCCAGGAACATTCTCTGGGGTTCTGCAGTGTTTGGTTTGTGATAAAACACTCCTGGGGAAAGA
GTCACTGCAGTGTTCTAACTGTAATGCAAATGTGCACAAAGGTTGTAAAGATGCTGCGCCTGCATGCACC
AAGAAATTCCAAGAGAAATATAACAAGAACAAACCACAGACCATCCTTGGAAATTCTTCATTTAGAGACA
TCCCACAGCCTGGTCTCTCCTTGCACCCTTCTTCCTCCGTGCCTGTTGGATTGCCGACTGGAAGGAGGGA
GACTGTGGGACAGGTCCATCCATTGTCCAGAAGTGTTCCAGGCACCACCTTGGAAAGCTTCAGGAGGTCA
GCCACATCCTTGGAGTCTGAGAGTGACCATAACAGCTGCAGAAGCAGGTCTCATTCTGATGAGCTGCTAC
AGTCCATGGGCTCTTCTCCCTCTACAGAGTCTTTCATAATGGAAGATGTTGTGGATTCTTCTCTGTGGAG
TGACCTCAGCAGTGATGCCCAGGAGTTTGAAGCAGAATCTTGGAGTCTTGTGGTGGATCCCTCATTTTGT
AATAGGCAGGAGAAGGATGTCATCAAAAGACAGGATGTCATTTTTGAGCTAATGCAAACAGAGATGCATC
ACATCCAGACCCTGTTCATCATGTCTGAGATCTTCAGGAAAGGCATGAAAGAGGAGCTGCAGCTGGACCA
CAGCACCGTGGATAAAATTTTCCCCTGTTTAGATGAGTTGCTTGAAATCCACAGGCATTTCTTCTACAGT
ATGAAGGAACGAAGGCAGGAATCCTGTGCTGGCAGCGACAGGAATTTTGTGATCGACCGAATTGGAGATA
TTTTGGTACAACAGTTTTCAGAAGAAAATGCAAGTAAAATGAAGAAAATATATGGAGAATTCTGTTGCCA
TCATAAAGAAGCTGTTAACCTCTTTAAAGAACTCCAGCAGAATAAAAAGTTTCAGAATTTTATTAAGCTC
CGAAATAGTAATCTTTTGGCTCGACGCCGAGGAATTCCAGAATGCATTCTGTTGGTCACTCAGCGTATTA
CAAAATACCCTGTCTTGGTGGAAAGGATATTGCAGTACACAAAGGAAAGAACTGAGGAACATAAAGACTT
ACGCAAAGCGCTTTGCTTAATTAAAGACATGATTGCAACAGTGGATTTAAAAGTCAATGAATATGAGAAA
AACCAAAAATGGCTTGAGATCCTAAATAAGATTGAAAACAAAACATACACGAAGCTCAAAAATGGACATG
TGTTTAGGAAGCAGGCACTGATGAGTGAAGAAAGGACTCTGTTATATGATGGCCTTGTTTACTGGAAAAC
TGCTACAGGTCGTTTCAAAGATATCCTAGCTCTACTTCTAACTGATGTGCTGCTCTTTTTACAAGAAAAA
GACCAGAAATACATCTTTGCAGCCGTTGATCAGAAGCCATCAGTTATTTCCCTTCAAAAGCTTATTGCTA
GAGAAGTTGCTAATGAGGAGAGAGGAATGTTTCTGATCAGTGCTTCATCTGCTGGTCCTGAGATGTATGA
AATTCACACCAATTCCAAGGAGGAACGCAATAACTGGATGAGACGGATCCAGCAGGCTGTAGAAAGTTGT
CCTGAAGAAAAAGGGGGAAGGACAAGTGAATCTGATGAAGACAAGAGGAAAGCTGAAGCCAGAGTGGCCA
AAATTCAGCAATGTCAAGAAATACTCACTAACCAAGACCAACAAATTTGTGCGTATTTGGAGGAGAAGCT
GCATATCTATGCTGAACTTGGAGAACTGAGCGGATTTGAGGACGTCCATCTAGAGCCCCACCTCCTTATT
AAACCTGACCCAGGCGAGCCTCCCCAGGCAGCCTCATTACTGGCAGCAGCACTGAAAGAAGCTGAGAGCC
TACAAGTTGCAGTGAAGGCCTCACAGATGGGCGCCGTGAGTCAATCATGTGAGGACAGTTGTGGAGACTC
TGTCTTGGCGGACACACTCAGTTCTCATGATGTACCAGGATCACCGACTGCCTCATTAGTCACAGGAGGG
AGAGAAGGAAGAGGCTGTTCGGATGTGGATCCCGGGATCCAGGGTGTGGTAACCGACTTGGCCGTCTCTG
ATGCAGGGGAGAAGGTGGAATGTAGAAATTTTCCAGGTTCTTCACAATCAGAGATTATACAAGCCATACA
GAATTTAACCCGTCTCTTATACAGCCTTCAGGCCGCCTTGACCATTCAGGACAGCCACATTGAGATCCAC
AGGCTGGTTCTCCAGCAGCAGGAGGGCCTGTCTCTCGGCCACTCTATCCTCCGAGGCGGCCCCTTGCAGG
ACCAGAAGTCTCGCGACGCGGACAGGCAGCATGAGGAGCTGGCCAATGTGCACCAGCTTCAGCACCAGCT
CCAGCAGGAGCAGCGGCGCTGGCTGCGCAGGTGTGAGCAGCAGCAGCGGGCGCAGGCGACCAGGGAGAGC
TGGCTGCAGGAGCGGGAGCGGGAGTGCCAGTCGCAGGAGGAGCTGCTGCTGCGGAGCCGGGGCGAGCTGG
ACCTCCAGCTCCAGGAGTACCAGCACAGCCTGGAGCGGCTGAGGGAGGGCCAGCGCCTGGTGGAGAGGGA
GCAGGCGAGGATGCGGGCCCAGCAGAGCCTGCTGGGCCACTGGAAGCACGGCCGGCAGAGGAGCCTGCCC
GCGGTGCTCCTTCCGGGTGGCCCCGAGGTAATGGAACTTAATCGATCTGAGAGTTTATGTCATGAAAACT
CATTCTTCATCAATGAAGCTTTAGTACAAATGTCATTTAACACTTTCAACAAACTGAATCCATCAGTTAT
CCATCAGGATGCCACTTACCCTACAACTCAATCTCATTCTGACTTGGTGAGGACTAGTGAACATCAAGTA
GACCTCAAGGTGGACCCTTCTCAGCCTTCGAATGTCAGTCACAAACTGTGGACAGCCGCTGGTTCCGGCC
ATCAGATACTTCCTTTCCATGAAAGCAGCAAGGATTCTTGTAAAAATGATTTGGACACCTCCCACACTGA
GTCCCCAACCCCCCATGACTCAAATTCACACCGCCCTCAACTGCAGGCGTTTATAACAGAAGCAAAGCTA
AATCTACCGACAAGGACAATGACCAGACAAGATGGGGAAACTGGAGATGGAGCCAAAGAAAATATTGTTT
ACCTCTAA