• accession：NM_006037
• 基因别名：HDAC4
• 基因描述：Homo sapiens histone deacetylase 4 (HDAC4), mRNA.
• 载体：现货载体
• CDS区长度：3255
• 翻译后氨基酸长度：1084
• 基因简介：Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGAGCTCCCAAAGCCATCCAGATGGACTTTCTGGCCGAGACCAGCCAGTGGAGCTGCTGAATCCTGCCC
GCGTGAACCACATGCCCAGCACGGTGGATGTGGCCACGGCGCTGCCTCTGCAAGTGGCCCCCTCGGCAGT
GCCCATGGACCTGCGCCTGGACCACCAGTTCTCACTGCCTGTGGCAGAGCCGGCCCTGCGGGAGCAGCAG
CTGCAGCAGGAGCTCCTGGCGCTCAAGCAGAAGCAGCAGATCCAGAGGCAGATCCTCATCGCTGAGTTCC
AGAGGCAGCACGAGCAGCTCTCCCGGCAGCACGAGGCGCAGCTCCACGAGCACATCAAGCAACAACAGGA
GATGCTGGCCATGAAGCACCAGCAGGAGCTGCTGGAACACCAGCGGAAGCTGGAGAGGCACCGCCAGGAG
CAGGAGCTGGAGAAGCAGCACCGGGAGCAGAAGCTGCAGCAGCTCAAGAACAAGGAGAAGGGCAAAGAGA
GTGCCGTGGCCAGCACAGAAGTGAAGATGAAGTTACAAGAATTTGTCCTCAATAAAAAGAAGGCGCTGGC
CCACCGGAATCTGAACCACTGCATTTCCAGCGACCCTCGCTACTGGTACGGGAAAACGCAGCACAGTTCC
CTTGACCAGAGTTCTCCACCCCAGAGCGGAGTGTCGACCTCCTATAACCACCCGGTCCTGGGAATGTACG
ACGCCAAAGATGACTTCCCTCTTAGGAAAACAGCTTCTGAACCGAATCTGAAATTACGGTCCAGGCTAAA
GCAGAAAGTGGCCGAAAGACGGAGCAGCCCCCTGTTACGCAGGAAAGACGGGCCAGTGGTCACTGCTCTA
AAAAAGCGTCCGTTGGATGTCACAGACTCCGCGTGCAGCAGCGCCCCAGGCTCCGGACCCAGCTCACCCA
ACAACAGCTCCGGGAGCGTCAGCGCGGAGAACGGTATCGCGCCCGCCGTCCCCAGCATCCCGGCGGAGAC
GAGTTTGGCGCACAGACTTGTGGCACGAGAAGGCTCGGCCGCTCCACTTCCCCTCTACACATCGCCATCC
TTGCCCAACATCACGCTGGGCCTGCCTGCCACCGGCCCCTCTGCGGGCACGGCGGGCCAGCAGGACGCCG
AGAGACTCACCCTTCCCGCCCTCCAGCAGAGGCTCTCCCTTTTCCCCGGCACCCACCTCACTCCCTACCT
GAGCACCTCGCCCTTGGAGCGGGACGGAGGGGCAGCGCACAGCCCTCTTCTGCAGCACATGGTCTTACTG
GAGCAGCCGCCGGCACAAGCACCCCTCGTCACAGGCCTGGGAGCACTGCCCCTCCACGCACAGTCCTTGG
TTGGTGCAGACCGGGTGTCCCCCTCCATCCACAAGCTGCGGCAGCACCGCCCACTGGGGCGGACCCAGTC
GGCCCCGCTGCCCCAGAACGCCCAGGCTCTGCAGCACCTGGTCATCCAGCAGCAGCATCAGCAGTTTCTG
GAGAAACACAAGCAGCAGTTCCAGCAGCAGCAACTGCAGATGAACAAGATCATCCCCAAGCCAAGCGAGC
CAGCCCGGCAGCCGGAGAGCCACCCGGAGGAGACGGAGGAGGAGCTCCGTGAGCACCAGGCTCTGCTGGA
CGAGCCCTACCTGGACCGGCTGCCGGGGCAGAAGGAGGCGCACGCACAGGCCGGCGTGCAGGTGAAGCAG
GAGCCCATTGAGAGCGATGAGGAAGAGGCAGAGCCCCCACGGGAGGTGGAGCCGGGCCAGCGCCAGCCCA
GTGAGCAGGAGCTGCTCTTCAGACAGCAAGCCCTCCTGCTGGAGCAGCAGCGGATCCACCAGCTGAGGAA
CTACCAGGCGTCCATGGAGGCCGCCGGCATCCCCGTGTCCTTCGGCGGCCACAGGCCTCTGTCCCGGGCG
CAGTCCTCACCCGCGTCTGCCACCTTCCCCGTGTCTGTGCAGGAGCCCCCCACCAAGCCGAGGTTCACGA
CAGGCCTCGTGTATGACACGCTGATGCTGAAGCACCAGTGCACCTGCGGGAGTAGCAGCAGCCACCCCGA
GCACGCCGGGAGGATCCAGAGCATCTGGTCCCGCCTGCAGGAGACGGGCCTCCGGGGCAAATGCGAGTGC
ATCCGCGGACGCAAGGCCACCCTGGAGGAGCTACAGACGGTGCACTCGGAAGCCCACACCCTCCTGTATG
GCACGAACCCCCTCAACCGGCAGAAACTGGACAGTAAGAAACTTCTAGGCTCGCTCGCCTCCGTGTTCGT
CCGGCTCCCTTGCGGTGGTGTTGGGGTGGACAGTGACACCATATGGAACGAGGTGCACTCGGCGGGGGCA
GCCCGCCTGGCTGTGGGCTGCGTGGTAGAGCTGGTCTTCAAGGTGGCCACAGGGGAGCTGAAGAATGGCT
TTGCTGTGGTCCGCCCCCCTGGACACCATGCGGAGGAGAGCACGCCCATGGGCTTTTGCTACTTCAACTC
CGTGGCCGTGGCAGCCAAGCTTCTGCAGCAGAGGTTGAGCGTGAGCAAGATCCTCATCGTGGACTGGGAC
GTGCACCATGGAAACGGGACCCAGCAGGCTTTCTACAGCGACCCCAGCGTCCTGTACATGTCCCTCCACC
GCTACGACGATGGGAACTTCTTCCCAGGCAGCGGGGCTCCTGATGAGGTGGGCACAGGGCCCGGCGTGGG
TTTCAACGTCAACATGGCTTTCACCGGCGGCCTGGACCCCCCCATGGGAGACGCTGAGTACTTGGCGGCC
TTCAGAACGGTGGTCATGCCGATCGCCAGCGAGTTTGCCCCGGATGTGGTGCTGGTGTCATCAGGCTTCG
ATGCCGTGGAGGGCCACCCCACCCCTCTTGGGGGCTACAACCTCTCCGCCAGATGCTTCGGGTACCTGAC
GAAGCAGCTGATGGGCCTGGCTGGCGGCCGGATTGTCCTGGCCCTCGAGGGAGGCCACGACCTGACCGCC
ATTTGCGACGCCTCGGAAGCATGTGTTTCTGCCTTGCTGGGAAACGAGCTTGATCCTCTCCCAGAAAAGG
TTTTACAGCAAAGACCCAATGCAAACGCTGTCCGTTCCATGGAGAAAGTCATGGAGATCCACAGCAAGTA
CTGGCGCTGCCTGCAGCGCACAACCTCCACAGCGGGGCGTTCTCTGATCGAGGCTCAGACTTGCGAGAAC
GAAGAAGCCGAGACGGTCACCGCCATGGCCTCGCTGTCCGTGGGCGTGAAGCCCGCCGAAAAGAGACCAG
ATGAGGAGCCCATGGAAGAGGAGCCGCCCCTGTAG

翻译后氨基酸参数序列： 点击查看序列

ATGAGCTCCCAAAGCCATCCAGATGGACTTTCTGGCCGAGACCAGCCAGTGGAGCTGCTGAATCCTGCCC
GCGTGAACCACATGCCCAGCACGGTGGATGTGGCCACGGCGCTGCCTCTGCAAGTGGCCCCCTCGGCAGT
GCCCATGGACCTGCGCCTGGACCACCAGTTCTCACTGCCTGTGGCAGAGCCGGCCCTGCGGGAGCAGCAG
CTGCAGCAGGAGCTCCTGGCGCTCAAGCAGAAGCAGCAGATCCAGAGGCAGATCCTCATCGCTGAGTTCC
AGAGGCAGCACGAGCAGCTCTCCCGGCAGCACGAGGCGCAGCTCCACGAGCACATCAAGCAACAACAGGA
GATGCTGGCCATGAAGCACCAGCAGGAGCTGCTGGAACACCAGCGGAAGCTGGAGAGGCACCGCCAGGAG
CAGGAGCTGGAGAAGCAGCACCGGGAGCAGAAGCTGCAGCAGCTCAAGAACAAGGAGAAGGGCAAAGAGA
GTGCCGTGGCCAGCACAGAAGTGAAGATGAAGTTACAAGAATTTGTCCTCAATAAAAAGAAGGCGCTGGC
CCACCGGAATCTGAACCACTGCATTTCCAGCGACCCTCGCTACTGGTACGGGAAAACGCAGCACAGTTCC
CTTGACCAGAGTTCTCCACCCCAGAGCGGAGTGTCGACCTCCTATAACCACCCGGTCCTGGGAATGTACG
ACGCCAAAGATGACTTCCCTCTTAGGAAAACAGCTTCTGAACCGAATCTGAAATTACGGTCCAGGCTAAA
GCAGAAAGTGGCCGAAAGACGGAGCAGCCCCCTGTTACGCAGGAAAGACGGGCCAGTGGTCACTGCTCTA
AAAAAGCGTCCGTTGGATGTCACAGACTCCGCGTGCAGCAGCGCCCCAGGCTCCGGACCCAGCTCACCCA
ACAACAGCTCCGGGAGCGTCAGCGCGGAGAACGGTATCGCGCCCGCCGTCCCCAGCATCCCGGCGGAGAC
GAGTTTGGCGCACAGACTTGTGGCACGAGAAGGCTCGGCCGCTCCACTTCCCCTCTACACATCGCCATCC
TTGCCCAACATCACGCTGGGCCTGCCTGCCACCGGCCCCTCTGCGGGCACGGCGGGCCAGCAGGACGCCG
AGAGACTCACCCTTCCCGCCCTCCAGCAGAGGCTCTCCCTTTTCCCCGGCACCCACCTCACTCCCTACCT
GAGCACCTCGCCCTTGGAGCGGGACGGAGGGGCAGCGCACAGCCCTCTTCTGCAGCACATGGTCTTACTG
GAGCAGCCGCCGGCACAAGCACCCCTCGTCACAGGCCTGGGAGCACTGCCCCTCCACGCACAGTCCTTGG
TTGGTGCAGACCGGGTGTCCCCCTCCATCCACAAGCTGCGGCAGCACCGCCCACTGGGGCGGACCCAGTC
GGCCCCGCTGCCCCAGAACGCCCAGGCTCTGCAGCACCTGGTCATCCAGCAGCAGCATCAGCAGTTTCTG
GAGAAACACAAGCAGCAGTTCCAGCAGCAGCAACTGCAGATGAACAAGATCATCCCCAAGCCAAGCGAGC
CAGCCCGGCAGCCGGAGAGCCACCCGGAGGAGACGGAGGAGGAGCTCCGTGAGCACCAGGCTCTGCTGGA
CGAGCCCTACCTGGACCGGCTGCCGGGGCAGAAGGAGGCGCACGCACAGGCCGGCGTGCAGGTGAAGCAG
GAGCCCATTGAGAGCGATGAGGAAGAGGCAGAGCCCCCACGGGAGGTGGAGCCGGGCCAGCGCCAGCCCA
GTGAGCAGGAGCTGCTCTTCAGACAGCAAGCCCTCCTGCTGGAGCAGCAGCGGATCCACCAGCTGAGGAA
CTACCAGGCGTCCATGGAGGCCGCCGGCATCCCCGTGTCCTTCGGCGGCCACAGGCCTCTGTCCCGGGCG
CAGTCCTCACCCGCGTCTGCCACCTTCCCCGTGTCTGTGCAGGAGCCCCCCACCAAGCCGAGGTTCACGA
CAGGCCTCGTGTATGACACGCTGATGCTGAAGCACCAGTGCACCTGCGGGAGTAGCAGCAGCCACCCCGA
GCACGCCGGGAGGATCCAGAGCATCTGGTCCCGCCTGCAGGAGACGGGCCTCCGGGGCAAATGCGAGTGC
ATCCGCGGACGCAAGGCCACCCTGGAGGAGCTACAGACGGTGCACTCGGAAGCCCACACCCTCCTGTATG
GCACGAACCCCCTCAACCGGCAGAAACTGGACAGTAAGAAACTTCTAGGCTCGCTCGCCTCCGTGTTCGT
CCGGCTCCCTTGCGGTGGTGTTGGGGTGGACAGTGACACCATATGGAACGAGGTGCACTCGGCGGGGGCA
GCCCGCCTGGCTGTGGGCTGCGTGGTAGAGCTGGTCTTCAAGGTGGCCACAGGGGAGCTGAAGAATGGCT
TTGCTGTGGTCCGCCCCCCTGGACACCATGCGGAGGAGAGCACGCCCATGGGCTTTTGCTACTTCAACTC
CGTGGCCGTGGCAGCCAAGCTTCTGCAGCAGAGGTTGAGCGTGAGCAAGATCCTCATCGTGGACTGGGAC
GTGCACCATGGAAACGGGACCCAGCAGGCTTTCTACAGCGACCCCAGCGTCCTGTACATGTCCCTCCACC
GCTACGACGATGGGAACTTCTTCCCAGGCAGCGGGGCTCCTGATGAGGTGGGCACAGGGCCCGGCGTGGG
TTTCAACGTCAACATGGCTTTCACCGGCGGCCTGGACCCCCCCATGGGAGACGCTGAGTACTTGGCGGCC
TTCAGAACGGTGGTCATGCCGATCGCCAGCGAGTTTGCCCCGGATGTGGTGCTGGTGTCATCAGGCTTCG
ATGCCGTGGAGGGCCACCCCACCCCTCTTGGGGGCTACAACCTCTCCGCCAGATGCTTCGGGTACCTGAC
GAAGCAGCTGATGGGCCTGGCTGGCGGCCGGATTGTCCTGGCCCTCGAGGGAGGCCACGACCTGACCGCC
ATTTGCGACGCCTCGGAAGCATGTGTTTCTGCCTTGCTGGGAAACGAGCTTGATCCTCTCCCAGAAAAGG
TTTTACAGCAAAGACCCAATGCAAACGCTGTCCGTTCCATGGAGAAAGTCATGGAGATCCACAGCAAGTA
CTGGCGCTGCCTGCAGCGCACAACCTCCACAGCGGGGCGTTCTCTGATCGAGGCTCAGACTTGCGAGAAC
GAAGAAGCCGAGACGGTCACCGCCATGGCCTCGCTGTCCGTGGGCGTGAAGCCCGCCGAAAAGAGACCAG
ATGAGGAGCCCATGGAAGAGGAGCCGCCCCTGTAG