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人 ARNT (NM_001197325) cDNA克隆
人 ARNT (NM_001197325) cDNA克隆
  • 商品货号:FC118173
  • 已售 7 件 | 评价 0 人次 | 关注度 382
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    • accession:NM_001197325
    • 基因别名:ARNT
    • 基因描述:Homo sapiens aryl hydrocarbon receptor nuclear translocator (ARNT), transcript variant 4, mRNA.
    • 载体:现货载体
    • CDS区长度:2322
    • 翻译后氨基酸长度:773
    • TranscriptVariant:This variant (4) lacks an alternate in-frame exon and uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
    • 基因简介:This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列