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- accession：NM_003645
- 基因别名：SLC27A2； VLCS; FATP2; VLACS; ACSVL1; FACVL1; hFACVL1; HsT17226
- 基因描述：Homo sapiens solute carrier family 27 (fatty acid transporter)， member 2 (SLC27A2)， transcript variant 1， mRNA.
- 载体：3×Flag-pLVX-TetOne-Puro
- CDS区长度：1863
- 翻译后氨基酸长度：620
- TranscriptVariant：This variant (1) represents the predominant transcript and encodes the longer isoform (1).
- 基因简介：The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity， subcellular localization， and tissue distribution， all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters， and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain， branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney， and is present in both endoplasmic reticulum and peroxisomes， but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq， Apr 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
