- accession:NM_001111112
- 基因别名:UBE2K
- 基因描述:Homo sapiens ubiquitin-conjugating enzyme E2K (UBE2K), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:474
- 翻译后氨基酸长度:157
- TranscriptVariant:This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
- 基因简介:The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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