×
![]()
- accession：NM_001172437
- 基因别名：PEG10
- 基因描述：Homo sapiens paternally expressed 10 (PEG10), transcript variant 2, mRNA.
- 载体：现货载体
- 翻译后氨基酸长度：784
- TranscriptVariant：This variant (2) uses an alternate donor splice site at the 5' terminal exon compared to variant 1, resulting in translation initiation from an in-frame, upstream AUG. It contains two overlapping reading frames, RF1 and RF1/RF2. This isoform (3), encoded by RF1/RF2, is longer with a distinct N-terminus compared to isoform 1, and is the product of -1 translational frame-shifting.
- 基因简介：This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010]
- 规格：10ul 质粒
翻译后氨基酸参数序列： 点击查看序列
