- accession:NM_017452
- 基因别名:STAU1
- 基因描述:Homo sapiens staufen double-stranded RNA binding protein 1 (STAU1), transcript variant T2, mRNA.
- 载体:现货载体
- CDS区长度:1491
- 翻译后氨基酸长度:496
- TranscriptVariant:This variant (T2) is most abundantly expressed, and encodes the protein isoform (a) of 496 amino acids.
- 基因简介:Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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