- accession:NM_016817
- 基因别名:OAS2
- 基因描述:Homo sapiens 2'-5'-oligoadenylate synthetase 2, 69/71kDa (OAS2), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:2160
- 翻译后氨基酸长度:719
- TranscriptVariant:This variant (1) encodes the longest isoform (1), which is also known as the p71 isoform.
- 基因简介:This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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