- accession:NM_001145320
- 基因别名:ADAMTSL2
- 基因描述:Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2856
- 翻译后氨基酸长度:951
- TranscriptVariant:This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
- 基因简介:This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列