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人 AKT2 (NM_001243027) cDNA克隆
人 AKT2 (NM_001243027) cDNA克隆
  • 商品货号:FC118988
  • 已售 5 件 | 评价 0 人次 | 关注度 228
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    • accession:NM_001243027
    • 基因别名:AKT2
    • 基因描述:Homo sapiens v-akt murine thymoma viral oncogene homolog 2 (AKT2), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:1260
    • 翻译后氨基酸长度:419
    • TranscriptVariant:This variant (2) differs in the 5' UTR, contains an alternate splice site in the 5' coding region, and initiates translation at a downstream AUG. This results in a protein (isoform 2) with a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode isoform 2.
    • 基因简介:This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列