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- accession：NM_000508
- 基因别名：FGA
- 基因描述：Homo sapiens fibrinogen alpha chain (FGA), transcript variant alpha-E, mRNA.
- 载体：现货载体
- CDS区长度：2601
- 翻译后氨基酸长度：866
- TranscriptVariant：This variant (alpha-E) represents the longer transcript and encodes the longer isoform (alpha-E).
- 基因简介：The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
