- accession:NM_139355
- 基因别名:MATK
- 基因描述:Homo sapiens megakaryocyte-associated tyrosine kinase (MATK), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1524
- 翻译后氨基酸长度:507
- TranscriptVariant:This variant (1) encodes the predominant isoform a.
- 基因简介:The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列