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人BAIAP2L1(NM_018842)ORF克隆
人BAIAP2L1(NM_018842)ORF克隆
  • 商品货号:FO108946
  • 已售 8 件 | 评价 0 人次 | 关注度 473
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    • accession:NM_018842
    • 基因别名:BAIAP2L1
    • 基因描述:Homo sapiens BAI1-associated protein 2-like 1 (BAIAP2L1), mRNA.
    • 载体: 现货载体
    • CDS区长度:1536
    • 翻译后氨基酸长度:511
    • 基因简介:This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq, Oct 2009]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列