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- accession：NM_000829
- 基因别名：GRIA4
- 基因描述：Homo sapiens glutamate receptor, ionotropic, AMPA 4 (GRIA4), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：2709
- 翻译后氨基酸长度：902
- TranscriptVariant：This variant (1) encodes the longest isoform (1). RNA editing (AGA->GGA) changes Arg765Gly.
- 基因简介：Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
