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人 HTR2A (NM_001165947) cDNA克隆
人 HTR2A (NM_001165947) cDNA克隆
  • 商品货号:FC121847
  • 已售 6 件 | 评价 0 人次 | 关注度 682
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    • accession:NM_001165947
    • 基因别名:HTR2A
    • 基因描述:Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled (HTR2A), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:1164
    • 翻译后氨基酸长度:387
    • TranscriptVariant:This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1, that causes translation initiation at an upstream AUG. The resulting protein (isoform 2) has a distinct N-terminus and is shorter than isoform 1.
    • 基因简介:This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列