- accession:NM_001165947
- 基因别名:HTR2A
- 基因描述:Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled (HTR2A), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1164
- 翻译后氨基酸长度:387
- TranscriptVariant:This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1, that causes translation initiation at an upstream AUG. The resulting protein (isoform 2) has a distinct N-terminus and is shorter than isoform 1.
- 基因简介:This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- 规格:10ul 质粒
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