- accession:NM_001134939
- 基因别名:OAZ3
- 基因描述:Homo sapiens ornithine decarboxylase antizyme 3 (OAZ3), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:0
- 翻译后氨基酸长度:190
- TranscriptVariant:This variant (2) contains an alternate 5' terminal exon compared to transcript variant 1, resulting in a shorter isoform (2) with a different N-terminus compared to isoform 1.
- 基因简介:Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
- 规格:10ul 质粒
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