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人 SMG6 (NM_001256828) cDNA克隆
人 SMG6 (NM_001256828) cDNA克隆
  • 商品货号:FC122204
  • 已售 6 件 | 评价 0 人次 | 关注度 346
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    • accession:NM_001256828
    • 基因别名:SMG6
    • 基因描述:Homo sapiens SMG6 nonsense mediated mRNA decay factor (SMG6), transcript variant 4, mRNA.
    • 载体:现货载体
    • CDS区长度:1536
    • 翻译后氨基酸长度:511
    • TranscriptVariant:This variant (4) uses an alternate internal promoter and thus differs in the 5' UTR and 5' coding region compared to variant 1. These differences cause translation initiation at a downstream AUG, and the resulting isoform (3) has a shorter N-terminus compared to isoform 1. Variants 3 and 4 encode the same protein (isoform 3).
    • 基因简介:This gene encodes a protein which is part of the telomerase ribonucleoprotein complex and binds single-stranded DNA found at the telomeres, but the product of this gene also participates in the nonsense-mediated mRNA decay (NMD) pathway. The encoded protein contains two binding sites for components of the exon junction complex (EJC); interaction between the encoded protein and the EJC is necessary for NMD activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列