×
![]()
- accession：NM_175721
- 基因别名：TPO
- 基因描述：Homo sapiens thyroid peroxidase (TPO), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：2670
- 翻译后氨基酸长度：889
- TranscriptVariant：This variant (4) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (d, also known as TPO4) compared to isoform a. This variant lacks the 5'-most non-coding exon because of alternate splicing, the extension at the 5' end is uncertain.
- 基因简介：This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
