- accession:NM_002420
- 基因别名:TRPM1
- 基因描述:Homo sapiens transient receptor potential cation channel, subfamily M, member 1 (TRPM1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:4812
- 翻译后氨基酸长度:1603
- TranscriptVariant:This variant (2) differs in the 5' UTR and lacks a portion of hte 5' coding region, compared to variant 1. These differences causes translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
- 基因简介:This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
- 规格:10ul 质粒
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