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人 ANGPT1 (NM_001146) cDNA克隆
人 ANGPT1 (NM_001146) cDNA克隆
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  • 商品货号:G120481
  • accession:NM_001146
  • 基因别名:ANGPT1
  • 基因描述:Homo sapiens angiopoietin 1 (ANGPT1), transcript variant 1, mRNA.
  • 载体:现货载体
  • CDS区长度:1497
  • 翻译后氨基酸长度:498
  • TranscriptVariant:This variant (1) represents the longer transcript and encodes the longer isoform (1).
  • 基因简介:Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列