- accession:NM_004381
- 基因别名:ATF6B
- 基因描述:Homo sapiens activating transcription factor 6 beta (ATF6B), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:2112
- 翻译后氨基酸长度:703
- TranscriptVariant:This variant (1) represents the longer transcript and encodes the longer isoform (a).
- 基因简介:The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列